BDBM50518821 CHEMBL4463217::US10829446, Compound 109

SMILES O=C(NNS(=O)(=O)c1ccccc1)c1cncc(c1)-c1ccccc1

InChI Key InChIKey=GSTUIJXFPBFFKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518821   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 50518821BDBM50518821(CHEMBL4463217 | US10829446, Compound 109)
Affinity DataIC50: 2.13E+4nMAssay Description:Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 50518821BDBM50518821(CHEMBL4463217 | US10829446, Compound 109)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed