BDBM50527305 CHEMBL4592414::US10829446, Compound 112

SMILES CCCOc1cc(F)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1

InChI Key InChIKey=FYQBFHKJLVHEEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527305   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527305BDBM50527305(CHEMBL4592414 | US10829446, Compound 112)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527305BDBM50527305(CHEMBL4592414 | US10829446, Compound 112)
Affinity DataIC50: 422nMAssay Description:Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent