BDBM50528615 CHEMBL4448829

SMILES C[C@H](CCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=GLXBRGHIMATFKV-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50528615   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528615BDBM50528615(CHEMBL4448829)
Affinity DataEC50:  38nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528615BDBM50528615(CHEMBL4448829)
Affinity DataEC50:  38nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528615BDBM50528615(CHEMBL4448829)
Affinity DataEC50:  480nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528615BDBM50528615(CHEMBL4448829)
Affinity DataEC50:  480nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed