BDBM50529576 CHEMBL4531460

SMILES Oc1cn2CCN(Cc3c(F)cccc3Cl)Cc2cc1=O

InChI Key InChIKey=CRHVGSLDKWWNAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529576   

TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529576(CHEMBL4531460)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529576(CHEMBL4531460)
Affinity DataIC50:  16nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed