BDBM50529931 CHEMBL4457172

SMILES OC(CNC(=O)c1cc2CN(Cc3ccccc3)CCc2s1)CN1CCc2ccccc2C1

InChI Key InChIKey=ARQXUJZVPOUYNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529931   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529931BDBM50529931(CHEMBL4457172)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529931BDBM50529931(CHEMBL4457172)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed