BDBM50531179 Methyl Carnosate

SMILES [H][C@@]12CCc3cc(C(C)C)c(O)c(O)c3[C@]1(CCCC2(C)C)C(=O)OC

InChI Key InChIKey=IIJLVJMZYPZQLW-YCRPNKLZSA-N

Data  8 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50531179   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  870nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  865nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  470nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataKd:  360nMAssay Description:Binding affinity to human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) by surface plasmon re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  470nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  870nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataKd:  360nMAssay Description:Binding affinity to human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) by surface plasmon re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531179(Methyl Carnosate)
Affinity DataIC50:  865nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed