BDBM50537951 Grifolic Acid
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#6])c(-[#6](-[#8])=O)c1-[#8]
InChI Key InChIKey=QPIZDZGIXDKCRC-JTCWOHKRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50537951
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human amyloid beta (1 to 40) aggregation after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated with substrate for 10 mi...More data for this Ligand-Target Pair