BDBM50538205 CHEMBL4636528
SMILES Fc1ccc(NC(=O)OCC2CCNCC2)c(c1)-c1ccc(F)c(Cl)c1
InChI Key InChIKey=GUWDPEQJYFKDCE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50538205
Affinity DataKi: 0.0640nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 0.0690nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor expressed in human HEK293T cell membranes by radioligand competition bindin...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor transiently expressed in HEK293T cell membranes incubated for 1 hr by scint...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Antagonist activity at muscarinic M3 receptor (unknown origin) expressed in HEK293 cells coexpressing EA tagged beta-arrestin2 assessed as inhibition...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in HEK293 cells assessed as increase in IP1 accumulation incubated for 90 min by TR-HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: 9.30nMAssay Description:Antagonist activity at human muscarinic M3 receptor expressed in HEK293 assessed as inhibition of carbachol-induced IP1 accumulation preincubated for...More data for this Ligand-Target Pair