BDBM50542380 CHEMBL4644380

SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(Cn4ccnn4)cc3c(=O)n-21

InChI Key InChIKey=WKUCZEJPWUVYSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542380   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542380(CHEMBL4644380)
Affinity DataIC50:  780nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542380(CHEMBL4644380)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli BL21 using L-Trp as substrate incubated for 30 mins by enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542380(CHEMBL4644380)
Affinity DataIC50:  80nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed