BDBM50553431 CHEMBL4754065

SMILES Cc1cc(ccc1CNC(=O)c1cnc(s1)C(C)(C)C)-c1ccnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=WRVOSJREZJCUSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553431   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553431(CHEMBL4754065)
Affinity DataIC50:  430nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in BTK phosphorylation measured after 30 mins by phosphotyrosine detection methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553431(CHEMBL4754065)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed