BDBM50553900 CHEMBL4750616
SMILES [Na;v0+].[#6]C([#6])([#8])c1coc(c1)S(=O)(=O)[#7-]-[#6](=O)-[#7]-c1c2-[#6]-[#6]-[#6]-c2cc2-[#6]-[#6]-[#6]-c12
InChI Key InChIKey=LFQQNXFKPNZRFT-UHFFFAOYSA-M
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50553900
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair