BDBM50553900 CHEMBL4750616

SMILES [Na;v0+].[#6]C([#6])([#8])c1coc(c1)S(=O)(=O)[#7-]-[#6](=O)-[#7]-c1c2-[#6]-[#6]-[#6]-c2cc2-[#6]-[#6]-[#6]-c12

InChI Key InChIKey=LFQQNXFKPNZRFT-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553900   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553900(CHEMBL4750616)
Affinity DataIC50:  30nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553900(CHEMBL4750616)
Affinity DataIC50:  28nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553900(CHEMBL4750616)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed