BDBM50559420 CHEMBL4784092

SMILES Cc1sc(cc1-n1cc(NC(=O)Nc2c(F)cccc2Cl)cn1)C(=O)NC1COC1

InChI Key InChIKey=JRCVTCDIBTUNEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50559420   

LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 53nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetMitogen-activated protein kinase 10(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 67nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 150nMAssay Description:Inhibition of JNK2 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of JNK3 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ATF2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetMitogen-activated protein kinase 8(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details