BDBM50561658 CHEMBL4799472
SMILES CNC(=O)c1csc2c(cc(nc12)N1CCN(CC1)C(C)C(=O)NC1CC1)C(F)(F)F
InChI Key InChIKey=OQBZQHVJNXTMMU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50561658
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair