BDBM50575287 CHEMBL4850902

SMILES O=C1CCCN1c1cnc(NCc2c(F)ccc3c2CCO3)c2cn[nH]c(=O)c12

InChI Key InChIKey=PONODDUVQSJBMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575287   

TargetPolycomb protein EED(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575287BDBM50575287(CHEMBL4850902)
Affinity DataIC50: 200nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575287BDBM50575287(CHEMBL4850902)
Affinity DataIC50: 210nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed