BDBM50575995 CHEMBL4560666

SMILES Cc1[nH]c2c(N3CCCCC3)c(nn2c(=O)c1-c1ccc(O)cc1)-c1ccccc1

InChI Key InChIKey=JDHPOXNOROPDTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575995   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Chia Tai Tianqing Pharmaceutical Co.

US Patent
LigandPNGBDBM50575995(CHEMBL4560666 | US20250186444, AGI-24512)
Affinity DataIC50: 26.8nMAssay Description:1. Experimental Stepsa) 5×MAT2A assay-buffer (250 mM Tris-HCl, pH 8.0; 250 mM KCl; 75 mM MgCl2; 0.025% BSA; 0.05% Brij35; 1.5 mM EDTA) were first pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetS-adenosylmethionine synthase isoform type-2(Human)
Nanjing Chia Tai Tianqing Pharmaceutical Co.

US Patent
LigandPNGBDBM50575995(CHEMBL4560666 | US20250186444, AGI-24512)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed