BDBM50580104 CHEMBL5083629

SMILES Oc1c(Cl)cccc1C(N1CCc2c1cc(OC(=O)Nc1ccccc1)cc2OC(=O)Nc1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=NBSJTAILDXZBAL-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580104   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  5.97E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  7.67E+3nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  4.19E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  1.92E+4nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed