BDBM50580104 CHEMBL5083629
SMILES Oc1c(Cl)cccc1C(N1CCc2c1cc(OC(=O)Nc1ccccc1)cc2OC(=O)Nc1ccccc1)c1ccc(F)cc1
InChI Key InChIKey=NBSJTAILDXZBAL-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50580104
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University
Curated by ChEMBL
Tampere University
Curated by ChEMBL
Affinity DataEC50: 5.97E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University
Curated by ChEMBL
Tampere University
Curated by ChEMBL
Affinity DataEC50: 7.67E+3nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University
Curated by ChEMBL
Tampere University
Curated by ChEMBL
Affinity DataEC50: 4.19E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Tampere University
Curated by ChEMBL
Tampere University
Curated by ChEMBL
Affinity DataEC50: 1.92E+4nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair