BDBM50581525 CHEMBL5088000
SMILES C[C@@H](Nc1ccn2ncc(-c3cnn(CCO)c3)c2n1)c1cc(F)ccc1OCC(F)F
InChI Key InChIKey=GYWAMONQPZXXDB-CYBMUJFWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50581525
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of wildtype TRKA (unknown origin) preincubated for 30 mins followed by biotinylated TK-peptide substrate addition and measured after 40 mi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of TRKA G667C mutant (unknown origin) preincubated for 30 mins followed by biotinylated TK-peptide substrate addition and measured after 4...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TRKA GS95R mutant (unknown origin) preincubated for 30 mins followed by biotinylated TK-peptide substrate addition and measured after 4...More data for this Ligand-Target Pair