BDBM50581550 AP-3152 FREE ACID::BMS-986020::Bms-986020

SMILES C[C@@H](OC(=O)Nc1c(C)noc1-c1ccc(cc1)-c1ccc(cc1)C1(CC1)C(O)=O)c1ccccc1

InChI Key InChIKey=GQBRZBHEPUQRPL-LJQANCHMSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50581550   

TargetCytochrome P450 2B6(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Induction of CYP2C9 in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine translocator ABCB4(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of MDR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of MRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  170nMAssay Description:Inhibition of OATP1B1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  570nMAssay Description:Inhibition of OATP1B3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of MRP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Induction of CYP2B6 in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50: >5.00E+4nMAssay Description:Induction of CYP3A4 in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581550(AP-3152 FREE ACID | BMS-986020 | Bms-986020)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of BSEP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed