BDBM50582454 CHEMBL5075646

SMILES ONC(=O)c1ccc(\C=C\c2ccnc(c2)-c2ccccc2O)cc1

InChI Key InChIKey=MCVBYWZUEUNVKU-AATRIKPKSA-N

Data  13 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50582454   

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  930nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 residues) (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 as substrate by amplex re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  47nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of human recombinant MAO-A by multimode plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  6.94E+4nMAssay Description:Inhibition of human recombinant MAO-B by multimode plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataKd:  3.83E+3nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  4.62E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  930nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  220nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  47nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582454(CHEMBL5075646)
Affinity DataIC50:  934nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed