BDBM50582677 CHEMBL5093811
SMILES OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1ccc(cc1)C(F)(F)F
InChI Key InChIKey=URJWPKRIWFUUQY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50582677
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 6.48E+3nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair