BDBM50591547 CHEMBL4534966

SMILES Fc1ccc(CN2CCc3cc(NS(=O)(=O)C4CCCCC4)ccc23)cc1

InChI Key InChIKey=XTMXYEVFULFOLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591547   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591547BDBM50591547(CHEMBL4534966)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed