BDBM50597430 DALZANEMDOR::Dalzanemdor

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@](C)(O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@](C)(O)C(F)(F)F

InChI Key InChIKey=BVBRUQYHUXKZMQ-UHFFFAOYSA-N

Data  14 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50597430   

TargetSodium channel protein type 5 subunit alpha(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of NaV1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataEC50:  430nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2D receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2C receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HCN2 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetKinesin-like protein KIF21A(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv1.5 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CaV1.2 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KCNQ1/MINK (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataEC50:  86nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 3A4(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 2D6(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 2C19(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 2C9(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 2C8(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 2B6(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetCytochrome P450 1A2(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed