BDBM50600732 CHEMBL5202191
SMILES CC(C)(F)c1nc(no1)C12CCC(CN(C(=O)[C@H]3C[C@@](C)(O)C3)c3cccc(c3)-c3ccc(cc3)C(C)(C)O)(CC1)CC2
InChI Key InChIKey=MYKBYRIJFGEXHC-BYXIYGGRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50600732
TargetBile acid receptor(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair