BDBM50603566 Benvitimod::GSK-2894512::GSK2894512::TAPINAROF::Tapinarof::Vtama::WBI-1001::Wbi-1001

SMILES CC(C)c1c(cc(cc1O)/C=C/c2ccccc2)O

InChI Key InChIKey=ZISJNXNHJRQYJO-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50603566   

TargetAryl hydrocarbon receptor(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603566BDBM50603566(TAPINAROF | Tapinarof | Benvitimod | Vtama | Wbi-1...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human AhR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAryl hydrocarbon receptor(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603566BDBM50603566(TAPINAROF | Tapinarof | Benvitimod | Vtama | Wbi-1...)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetAryl hydrocarbon receptor(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603566BDBM50603566(TAPINAROF | Tapinarof | Benvitimod | Vtama | Wbi-1...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAryl hydrocarbon receptor(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603566BDBM50603566(TAPINAROF | Tapinarof | Benvitimod | Vtama | Wbi-1...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at AHR in human HepG2-Lucia AhR cells stably transfected with DRE by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)