BDBM50605867 CHEMBL469045

SMILES C[C@]12CC/C(=N\OCCN)/C[C@@H]1C(=O)C[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C

InChI Key InChIKey=MPYLDWFDPHRTEG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605867   

LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMAssay Description:Na,K-ATPase activity was assayed in vitro by measuring the release of 32P-ATP, as described previously (see Ferrandi M. et al., Hypertension 1996; 28...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMAssay Description:Inhibition of Beagle dog kidney NA+/K+ ATPase alpha 1 by measuring 32P-ATP hydrolysis preincubated for 10 mins followed by addition of 32P-ATP measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)