BDBM50606748 CHEMBL5218582

SMILES C[C@H]1CN(CCN1C(=O)c1cc(CN2CCN(CC2)c2ccccc2Cl)c(C)n1C)c1cccc(F)c1C#N

InChI Key InChIKey=IJKMMCIUUSMYJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606748   

TargetTarget of rapamycin complex subunit LST8(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606748BDBM50606748(CHEMBL5218582)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human MCF7 cells assessed as measuring phosphorylated S6K1 incubated for 2 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606748BDBM50606748(CHEMBL5218582)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORC2 in human MCF7 cells assessed as measuring phosphorylated AKT incubated for 2 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed