BDBM50607733 CHEMBL5219642

SMILES CC(C)[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCCC[C@H](NC(=O)[C@H](Cc2ccc(cc2)[N+]([O-])=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(N)=O

InChI Key InChIKey=UWUBSFPMKFWHGU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607733   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607733BDBM50607733(CHEMBL5219642)
Affinity DataKi:  6.60E+4nMAssay Description:Binding affinity to PRMT5/MEP50 (unknown origin) assessed as inhibition constant by FITC- Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607733BDBM50607733(CHEMBL5219642)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) incubated for 1 to 2 hrs in presence of tracer 50 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed