BDBM50608082 CHEMBL5265919

SMILES Cn1cnc(c1-c1ccncc1)-c1ccccc1

InChI Key InChIKey=NSJCXUONRHOYTD-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50608082   

TargetHistone-lysine N-methyltransferase NSD3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608082(CHEMBL5265919)
Affinity DataIC50: 203nMAssay Description:Inhibition of GST-tagged NSD3 (247 to 398 residues) (unknown origin) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608082(CHEMBL5265919)
Affinity DataKd:  1.60E+5nMAssay Description:Binding affinity to recombinant human NSD3 PWWP1 domain (247 to 398 residues) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608082(CHEMBL5265919)
Affinity DataKd:  1.60E+5nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50608082(CHEMBL5265919)
Affinity DataKd:  1.60E+5nMAssay Description:Binding affinity to human NSD3 PWWP1 domain (247 to 398 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed