BDBM50609670 CHEMBL5277468

SMILES CC(C)(C(=O)Nc1ccc(cc1)-c1cccnc1)c1csc(NS(=O)(=O)C2CC2)n1

InChI Key InChIKey=DPLOYGIYFRQQBR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50609670   

TargetCTP synthase 1(Homo sapiens)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of C-terminal FLAG-His8-tagged full length human CTPS1 preincubated for 10 mins followed by substrate addition by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 2(Homo sapiens)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  242nMAssay Description:Inhibition of human CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Mus musculus)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  53nMAssay Description:Inhibition of mouse CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 2(Rattus norvegicus)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  35nMAssay Description:Inhibition of rat CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 2(Mus musculus)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  113nMAssay Description:Inhibition of mouse CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Homo sapiens)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed