BDBM50614981 CHEMBL5284493

SMILES Cc1ccc(cc1)[C@H]([C@@H](C)C(=O)O)NC(=O)[C@H](c2ccc3c(c2)CCCC3)F

InChI Key InChIKey=MQNFGUOKPYSZBX-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50614981   

TargetKelch-like ECH-associated protein 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50614981(CHEMBL5284493)
Affinity DataIC50: 89nMAssay Description:Inhibition of Nrf2-Keap1 Kelch domain (unknown origin) protein-protein interaction in presence of biotin labeled 16mer ETGE peptide AFFAQLQLDEETGEFLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50614981(CHEMBL5284493)
Affinity DataKd:  130nMAssay Description:Binding affinity to biotinylated Keap1 Kelch domain (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50614981(CHEMBL5284493)
Affinity DataIC50: 260nMAssay Description:Inhibition of His-tagged human Keap1 Kelch domain /FITC-labelled-9mer Nrf2 (unknown origin) protein-protein interaction incubated for 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details