BDBM50630142 CHEMBL5435388

SMILES c1ccc2c(c1)c3c(ccn3Cc4cccc(c4)Cl)c(n2)N5CCNCC5

InChI Key InChIKey=MFUVKDHSDIAPMH-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630142   

Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630142BDBM50630142(CHEMBL5435388)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-LSD from human 5HT-6 receptor expressed in HEK293 cell membranes assessed as inhibition constant measured after 1 hr by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630142BDBM50630142(CHEMBL5435388)
Affinity DataIC50: 5.28E+5nMAssay Description:Antagonist activity at mouse 5-HT3 receptor expressed in xenopus oocytes assessed as inhibition of 5-HT-induced inward currents incubated for 2 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Mus musculus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630142BDBM50630142(CHEMBL5435388)
Affinity DataIC50: 6.95E+5nMAssay Description:Antagonist activity at mouse 5-HT3 receptor expressed in xenopus oocytes assessed as inhibition of 5-HT-induced inward currents incubated for 2 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)