BDBM50635378 CHEMBL5558057

SMILES Cc1cc(nc(n1)SCC(=O)Nc2ncc(s2)Cc3cccc(c3)OCc4cn(nn4)Cc5ccc(cc5)OCCN6CCOCC6)C

InChI Key InChIKey=CTNBHQJETORMIL-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50635378   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Freiburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635378BDBM50635378(CHEMBL5558057)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Sirt2 (56 to 356 residues) deacetylation expressed in Escherichia coli BL21 (DE3) using ZMAL as substrate incubated for 4 hrs in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Freiburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635378BDBM50635378(CHEMBL5558057)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human Sirt2 (56 to 356 residues) demyristoylation expressed in Escherichia coli BL21 (DE3) using ZMML as substrate incubated for 4 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)