BDBM50642698 CHEMBL5574322

SMILES CCC1=NN(C(=O)c2n1c3ccsc3c2)CC(=O)Nc4ccncn4

InChI Key InChIKey=CWNJFZLUBUHIRK-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50642698   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642698BDBM50642698(CHEMBL5574322)
Affinity DataIC50: 104nMAssay Description:Inhibition of NLRP3 in PMA-differentiated human THP-1 cells assessed as reduction in IL-1beta release preincubated with compound for 1 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)