BDBM50643 1H-Benzo[a]carbazole-1,4(11H)-dione, 8-methoxy-11- methyl-::8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione::8-methoxy-11-methyl-benzo[a]carbazole-1,4-quinone::8-methoxy-11-methylbenzo[a]carbazole-1,4-dione::MLS000756809::SMR000529077::cid_369539

SMILES COc1ccc2n(C)c3c4C(=O)C=CC(=O)c4ccc3c2c1

InChI Key InChIKey=NJELFFLROCNKMT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50643   

LigandChemical structure of BindingDB Monomer ID 50643BDBM50643(8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione | ...)
Affinity DataIC50: 946nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCaspase-9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50643BDBM50643(8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione | ...)
Affinity DataIC50: 1.66E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2012
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50643BDBM50643(8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione | ...)
Affinity DataIC50: 1.93E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643BDBM50643(8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione | ...)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50643BDBM50643(8-methoxy-11-methyl-benzo[a]carbazole-1,4-dione | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay