BDBM508567 2,2-difluoro-8-{2-[(3R)-3- phenylpyrrolidin-1- yl]ethyl}[1,3]dioxolo[4,5- h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 37

SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CC[C@@H](C3)c3ccccc3)nn12

InChI Key InChIKey=HDJZIOUSIOKJMD-AWEZNQCLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508567   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508567(2,2-difluoro-8-{2-[(3R)-3- phenylpyrrolidin-1- yl...)
Affinity DataKi:  20nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent