BDBM508654 (R or S)-8-[2-(3,3-difluoroazetidin- 1-yl)propyl]-2,2-difluoro[1,3] dioxolo[4,5-h][1,2,4]triazolo[1,5-c] quinazolin-5-amine (faster eluting b)::US11046714, Example 93::US11046714, Example 94

SMILES CC(Cc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1)N1CC(F)(F)C1

InChI Key InChIKey=ILIXALIZILTPHR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508654   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508654((R or S)-8-[2-(3,3-difluoroazetidin- 1-yl)propyl]-...)
Affinity DataKi:  4.10nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508654((R or S)-8-[2-(3,3-difluoroazetidin- 1-yl)propyl]-...)
Affinity DataKi:  4.80nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent