BDBM509035 US11071730, Example 142

SMILES CC(C)n1cnc2cc(nc(Nc3ccncc3F)c12)-c1ccc2c(c1)N(C1CC(C1)N1CCCCC1)C(=O)C21CCN(CC1)C(=O)C1(CC1)C#N

InChI Key InChIKey=WSPAPDOCHFPQEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 509035   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM509035(US11071730, Example 142)
Affinity DataIC50: 0.300nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
Go to US Patent