BDBM510069 N-(cycloheptylmethyl)- 8-oxo-5,6,7,8-tetrahydro- quinoline-5-carboxamide::US11077100, Example 5::US11439633, Example 5

SMILES O=C(NCC1CCCCCC1)C1CCC(=O)c2ncccc12

InChI Key InChIKey=LCCXTNQSDIXHRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510069   

TargetP2X purinoceptor 7(Human)
Raqualia Pharma

US Patent
LigandPNGBDBM510069(N-(cycloheptylmethyl)- 8-oxo-5,6,7,8-tetrahydro- q...)
Affinity DataIC50: 2.00E+3nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Raqualia Pharma

US Patent
LigandPNGBDBM510069(N-(cycloheptylmethyl)- 8-oxo-5,6,7,8-tetrahydro- q...)
Affinity DataIC50: 2.00E+3nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent