BDBM510462 (5S,8S)-N- (4-chloro-2,3- difluorobenzyl)- 5-fluoro- 8-hydroxy-8- (hydroxymethyl)- 5,6,7,8- tetrahydroquinoline- 5-carboxamide::US11077100, Example 322

SMILES OC[C@]1(O)CC[C@@](F)(C(=O)NCc2ccc(Cl)c(F)c2F)c2cccnc12

InChI Key InChIKey=AQWRHIBTCZZTAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510462   

TargetP2X purinoceptor 7(Human)
Raqualia Pharma

US Patent
LigandPNGBDBM510462((5S,8S)-N- (4-chloro-2,3- difluorobenzyl)- 5-fluor...)
Affinity DataIC50: 200nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent