BDBM5113 N-(5-Acetyl-3,4-dimethyl-1,3-thiazol-2(3H)-ylidene)-3-nitrobenzenesulfonamide::N-[(2Z)-5-acetyl-3,4-dimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]-3-nitrobenzene-1-sulfonamide::thiazolidenebenzenesulfonamide deriv. 17f

SMILES CC(=O)c1sc(=NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C

InChI Key InChIKey=ZVTXDIONNNQVKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5113   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5113(N-[(2Z)-5-acetyl-3,4-dimethyl-2,3-dihydro-1,3-thia...)
Affinity DataIC50: 5.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5113(N-[(2Z)-5-acetyl-3,4-dimethyl-2,3-dihydro-1,3-thia...)
Affinity DataIC50: 5.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5113(N-[(2Z)-5-acetyl-3,4-dimethyl-2,3-dihydro-1,3-thia...)
Affinity DataIC50: 5.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed