BDBM511446 (3-amino-1-(4-(1-(phenethoxyimino)ethyl)benzoyl)pyrrolidin-3-yl)methyl Dihydrogen Phosphate::US11059784, Example 55

SMILES CC(=NOCCc1ccccc1)c1ccc(cc1)C(=O)N1CCC(N)(COP(O)(O)=O)C1

InChI Key InChIKey=RIUOPVXMDZXDIR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511446   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511446((3-amino-1-(4-(1-(phenethoxyimino)ethyl)benzoyl)py...)
Affinity DataEC50:  1.56E+3nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in an 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or ED...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511446((3-amino-1-(4-(1-(phenethoxyimino)ethyl)benzoyl)py...)
Affinity DataEC50: >6.00E+4nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in an 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or ED...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent