BDBM512121 (1R,3S,5R)-2-(2-(3- acetyl-6-fluoro-5-(2- methylpyrimidin-5- yl)-1H-indol-1- yl)acetyl)-N-(6- bromo-3- methylpyridin-2-yl)-5- methyl-2- azabicyclo[3.1.0]hexane- 3-carboxamide::US11084800, Cpd No. 482::US11708351, Compound 482

SMILES CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@]3(C)C[C@H]2C(=O)Nc2nc(Br)ccc2C)c2cc(F)c(cc12)-c1cnc(C)nc1

InChI Key InChIKey=JABGENUPGHRTFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512121   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512121(US11084800, Cpd No. 482 | (1R,3S,5R)-2-(2-(3- acet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512121(US11084800, Cpd No. 482 | (1R,3S,5R)-2-(2-(3- acet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent