BDBM512258 US11084800, Cpd No. 490::US11708351, Compound 490

SMILES CNCCNC(=O)c1nn(CC(=O)N2[C@@H]3C[C@]3(C)C[C@H]2C(=O)Nc2nc(Br)ccc2C)c2ccc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=MRPDOTPEKVBJDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512258   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512258(US11084800, Cpd No. 490 | US11708351, Compound 490)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512258(US11084800, Cpd No. 490 | US11708351, Compound 490)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent