BDBM513731 US11091495, Example 92::US11220509, Example 92::US11485738, Example 92

SMILES Cc1nn(C(C)C)c(C)c1c4cnc(NCc3c(F)ccc2OCCc23)n5cc(C#N)nc45

InChI Key InChIKey=JCFPVARYWWHQNE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513731   

LigandChemical structure of BindingDB Monomer ID 513731BDBM513731(US11220509, Example 92 | US11091495, Example 92 | ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513731BDBM513731(US11220509, Example 92 | US11091495, Example 92 | ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513731BDBM513731(US11220509, Example 92 | US11091495, Example 92 | ...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513731BDBM513731(US11220509, Example 92 | US11091495, Example 92 | ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent