BDBM513796 US11091495, Example 157

SMILES Cn1nc(C(=O)O)cc1c4cnc(NCc3c(F)ccc2OCCc23)n5cc(C#N)nc45

InChI Key InChIKey=AFEKNNXNWROLRP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513796   

LigandChemical structure of BindingDB Monomer ID 513796BDBM513796(US11091495, Example 157 | US20240398811, Example 1...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513796BDBM513796(US11091495, Example 157 | US20240398811, Example 1...)
Affinity DataIC50: 100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513796BDBM513796(US11091495, Example 157 | US20240398811, Example 1...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513796BDBM513796(US11091495, Example 157 | US20240398811, Example 1...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent