BDBM513862 US11091495, Example 224::US11220509, Example 224::US11485738, Example 224

SMILES Cn1cc(c(n1)C#N)-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N

InChI Key InChIKey=DAVDIQRPWGWPFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513862   

LigandChemical structure of BindingDB Monomer ID 513862BDBM513862(US11220509, Example 224 | US11091495, Example 224 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513862BDBM513862(US11220509, Example 224 | US11091495, Example 224 ...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513862BDBM513862(US11220509, Example 224 | US11091495, Example 224 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513862BDBM513862(US11220509, Example 224 | US11091495, Example 224 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent