BDBM513870 8-(4-bromo-1H-pyrazol-3-yl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile::US11091495, Example 232::US11220509, Example 232::US11485738, Example 232

SMILES N#Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3n[nH]cc3Br)c2n1

InChI Key InChIKey=QJOCJQZOHIWCTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 513870   

LigandChemical structure of BindingDB Monomer ID 513870BDBM513870(US11220509, Example 232 | US11091495, Example 232 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513870BDBM513870(US11220509, Example 232 | US11091495, Example 232 ...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 513870BDBM513870(US11220509, Example 232 | US11091495, Example 232 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent