BDBM515818 US11053225, Compound 93

SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCN(Cc2c1)C(=O)C(F)(F)F

InChI Key InChIKey=LCZJQUXLNMYSLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515818   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515818(US11053225, Compound 93)
Affinity DataIC50: 28nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515818(US11053225, Compound 93)
Affinity DataIC50: 1.90E+3nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515818(US11053225, Compound 93)
Affinity DataIC50: 240nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent