BDBM517326 1-(4-fluorophenyl)-3-(3- methoxyphenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-1H-indazole-6- carboxamide (enantiomer A)::US11104690, Example 144-A

SMILES COc1cccc(c1)-c1nn(-c2ccc(F)cc2)c2cc(ccc12)C(=O)N[C@]1(C)CCS(=O)(=O)C1

InChI Key InChIKey=RNDYKEZVDBZRTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517326   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517326(US11104690, Example 144-A | 1-(4-fluorophenyl)-3-(...)
Affinity DataIC50: 5.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent