BDBM517362 1-(4-fluorophenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-3-[2- (trifluoromethyl)pyridin-4- yl]-1H-indazole-6- carboxamide (enantiomer A)::US11104690, Example 159-A

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1ccnc(c1)C(F)(F)F

InChI Key InChIKey=AXFIGZXAWWFJIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517362   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517362(US11104690, Example 159-A | 1-(4-fluorophenyl)-N-(...)
Affinity DataIC50: 469nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent